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| Results | For | Against | Difference | Record | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Team | G | W | D | L | % | Tot | Ave | Tot | Ave | Tot | Ave | Home | Away |
| 2010 FBS (Division 1-A) | 10 | 5 | 0 | 5 | 0.500 | 262 | 26.20 | 194 | 19.40 | 68 | 6.80 | 3-3 | 2-2 |
NCAA Football 2010 FBS (Division 1-A)Completed | ||||||||||||
| 1 | 4 Sep 2010 @ 12:30 | Louisville Cardinals |  | 16 | - | 23 |  | Kentucky Wildcats | M | NCAA Football2010-09-04T12:30:00-07:00Louisville Cardinals v Kentucky Wildcats | Papa John's Cardinal Stadium, Louisville, KY, USA | |
| 2 | 11 Sep 2010 @ 12:30 | Louisville Cardinals |  | 23 | - | 13 |  | Eastern Kentucky Colonels | M | NCAA Football2010-09-11T12:30:00-07:00Louisville Cardinals v Eastern Kentucky Colonels | Papa John's Cardinal Stadium, Louisville, KY, USA | |
| 3 | 18 Sep 2010 @ 14:30 | Oregon State Beavers |  | 35 | - | 28 |  | Louisville Cardinals | M | NCAA Football2010-09-18T14:30:00-07:00Oregon State Beavers v Louisville Cardinals | Reser Stadium, Corvallis, OR, USA | |
| 5 | 2 Oct 2010 @ 16:00 | Arkansas State Red Wolves |  | 24 | - | 34 |  | Louisville Cardinals | M | NCAA Football2010-10-02T16:00:00-07:00Arkansas State Red Wolves v Louisville Cardinals | ASU Stadium, Jonesboro, AR, USA | |
| 6 | 9 Oct 2010 @ 11:00 | Louisville Cardinals | | 56 | - | 0 |  | Memphis Tigers | M | NCAA Football2010-10-09T11:00:00-07:00Louisville Cardinals v Memphis Tigers | Papa John's Cardinal Stadium, Louisville, KY, USA | |
| 7 | 15 Oct 2010 @ 17:00 | Louisville Cardinals | | 27 | - | 35 |  | Cincinnati Bearcats | M | NCAA Football2010-10-15T17:00:00-07:00Louisville Cardinals v Cincinnati Bearcats | Papa John's Cardinal Stadium, Louisville, KY, USA | |
| 8 | 23 Oct 2010 @ 12:30 | Louisville Cardinals | | 26 | - | 0 |  | Connecticut Huskies | M | NCAA Football2010-10-23T12:30:00-07:00Louisville Cardinals v Connecticut Huskies | Papa John's Cardinal Stadium, Louisville, KY, USA | |
| 9 | 30 Oct 2010 @ 09:00 | Pittsburgh Panthers |  | 20 | - | 3 | | Louisville Cardinals | M | NCAA Football2010-10-30T09:00:00-07:00Pittsburgh Panthers v Louisville Cardinals | Heinz Field, Pittsburgh, PA, USA | |
| 10 | 6 Nov 2010 @ 09:00 | Syracuse Orange |  | 20 | - | 28 | | Louisville Cardinals | M | NCAA Football2010-11-06T09:00:00-07:00Syracuse Orange v Louisville Cardinals | Carrier Dome, Syracuse, NY, USA | |
| 11 | 13 Nov 2010 @ 08:00 | Louisville Cardinals | | 21 | OT | 24 |  | South Florida Bulls | M | NCAA Football2010-11-13T08:00:00-08:00Louisville Cardinals v South Florida Bulls | Papa John's Cardinal Stadium, Louisville, KY, USA | |
| 12 | 20 Nov 2010 @ TBA | Louisville Cardinals | | Vs |  | West Virgina Mountaineers | M | NCAA Football2010-11-20T08:34:00-08:00Louisville Cardinals v West Virgina Mountaineers | Papa John's Cardinal Stadium, Louisville, KY, USA | |||
| 13 | 26 Nov 2010 @ TBA | Rutgers Scarlet Knights |  | Vs | | Louisville Cardinals | M | NCAA Football2010-11-26T08:34:00-08:00Rutgers Scarlet Knights v Louisville Cardinals | Rutgers Stadium, Piscataway, NJ, USA | |||
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